SEVERE ORGANOPHOSPHATE POISONING WITH DELAYED CHOLINERGIC CRISIS, INTERMEDIATE SYNDROME AND ORGANOPHOSPHATE INDUCED DELAYED POLYNEUROPATHY ON SUCCESSION

Abstract

Organophosphate compounds are the organic derivatives of Phosphorous containing acids and their
effect on neuromuscular junction and Autonomic Synapses is clinically important. After exposure these
agents cause acute and sub acute manifestations depending on the type and severity of the agents like
Acute Cholinergic Manifestations, Intermediate Syndrome with Nicotinic features and Delayed Central
Nervous System Complications. The patient reported here had severe Organophosphate Poisoning with
various rare complications on a succession. This is the first report of Organophosphates Poisoning
complicated by Intermediate Syndrome and Organophosphate Induced Delayed Polyneuropathy in
Ethiopia and it is reported to increase awareness of health care workers on these rare complications of a
common problem.